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During that same time span, the number of people with no insurance coverage for another GLP-1 receptor agonist, Zepbound, increased by 14%, which meant that another 4.9 million or so more people were bound for no insurance coverage for the tirzepatide-containing Zepbound

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In all in vitro and in vivo models used, tirzepatide was able to stimulate glucose-dependent insulin secretion via GIP and/or GLP-1 receptor activation